close
CBD

CBD dossier: What is cannabidiol?

How did the famous second component of cannabis, CBD, become a symbol of health?

In a context of research and legality in many countries, its percentage of use by inhalation, oil, cosmetics, food supplements is increasing day by day. On the other hand, there are those who are already working to define it as “medicine”, which could completely stop the current free trade?

Better understand certain confusions

THC, identified in 1964 by Professor Rafael Meshoulam, is much better known and more famous than its non-psychoactive brother the cannabidiole aka CBD. The latter was identified earlier in the 1940s by Doctor Roger Adams as well as his cannabinoid "little brother" CBN.

Among the 133 cannabinoids identified so far, CBD has the particularity, by consuming it, of connecting to special receptors: the endocannabinoid system (CB1 and CB2). It attaches itself to the most important organs of the human body such as the brain, spinal cord, digestive system as well as a host of other organs. This acts on the action of said organs but also on human health, so that science is still not able to fully understand it.

Difference between THC & CBD

2 Types of hemp

Industrial hemp and medical hemp known as cannabis each produce CBD, but not in the same amount. Recent studies on the benefits of this component have led to the development of cannabis species rich in CBD. These plants are able to reach a content of 15% compared to hemp plants which are generally between 2% to 4%

These two categories are used to produce oils, creams, capsules, mineral water and even crystal extracts containing up to 99% CBD.

The most obvious advantage of CBD is that it is not psychoactive, at least for those who are not interested in the “high” of a joint. It is much more user-friendly and easily integrates into a normative lifestyle.

This is a double advantage, since its nature directly and clearly affects its diffusion, this innocent molecule is considered to be perfectly legal.

Countries have allowed its use by allowing the use of hemp: the strain of industrial cannabis that contains only a few percent of THC and is thus used to produce food and industrial products.

How to use CBD crystal

New revelations about its therapeutic abilities have made cannabidiol more popular. Today, many entrepreneurs and consumers are joining in what appears to be a real revolution in the use of the components of cannabis that do not cause a high.

In the not too distant future, CBD will have become an essential source which will enter into the composition of food products, in food supplements and also in the composition of pharmaceutical specialties.

However, according to the above studies and according to experts in this field, CBD alone does not have the same health benefits compared to all of cannabis with all its components (THC + CBD). The phenomenon known as the entourage effect has been shown to be the most important for the complete and successful treatment of cannabis, although CBD has its specific advantages in simple use.

Your next medicine?

Among others, cannabidiol, over the years, reveals its most varied qualities such as the reduction of epileptic seizures, severe analgesia, treatment of diabetes, treatment of schizophrenia, stops the development of cancerous tumors, treats the anxiety, relieves nausea and vomiting, treats migraines, has anti-inflammatory properties and more even see the potential to renew cells in the brain in a process called neurogenesis.

New research recently published has found another benefit: CBD has an important ability to balance the psychoactive effects of THC and to prevent phenomena such as paranoia and worry due to overmedicalization.

The company currently leading the most advanced clinical research in CBD is UK pharmaceutical company GW Pharmaceuticals, renowned cannabis spray maker Sativex, which is currently working on the final stages of the development of its new flagship product, Epidiolex, which acts like Sativex but contains no THC but only 98% CBD and 2% other cannabinoids.

Big Cannabis or the sad advent of GM grass

GW recently announced the success of the Phase 3 trial of Epidiolex as a treatment for people with epilepsy and LGS (Lennox-Gastaut syndrome): a particularly acute form of epilepsy. The study found that the company's CBD oil reduced the amount and intensity of tremors and spasms experienced by people with the condition by 42%.

Following the success of the study with CBD in epilepsy, GW recently filed an official request with the FDA for approval of its new drug. If Epidiolex is approved as a drug, GW is expected to earn billions of dollars from global sales.

Georgia expands medical program

Elsewhere, in Israel, CBD oil given to children with epilepsy and autism have shown success in 75% of cases, almost twice the numbers presented by GW. "Today we have thousands of patients whose lives have revolutionized CBD, including hundreds of children with epilepsy, children with autism, 75% of whom report significant improvement," said Aaron Lutzky of Tikkun Olam. leader in global cannabis.

to read :  CBD oil for children with epilepsy

A food supplement?

The direction taken by CBD towards the pharma world also creates legal problems in its relatively free marketing under the definition of "dietary supplement". Authorities recently determined in the United States and Great Britain that CBD has medical value and therefore may be banned for sale by companies that are not licensed pharmaceutical companies.

Therefore, many in the industry are now concerned that this will lead to the revocation of the license to use CBD as a "food additive" which allows free trade and will completely ban its sale and marketing.

As part of this activity, the FDA regularly sends out warning letters to sites offering CBD for sale. Letters are sent to companies that advertise on their websites or brochures about their CBD products believing that it is a product of medical value, which can cure various diseases and reduce cancerous tumors, for example.

Like the FDA, its counterpart in the United Kingdom, the Health and Drug Administration Agency (MHRA) has announced that it is examining the issue of defining CBD as a drug: a move that would ban its sale as a dietary supplement altogether. “The change came when we expressed the position that CBD is indeed a drug,” said (on Sky News) Gerald Huddle, The Director of Supervision and Control of the British Agency.

To this day, as long as the seller does not declare that it is a therapeutic or medicinal product with therapeutic properties, cannabidiol is still allowed to be sold according to the definition of "dietary supplement". At the same time, a behind-the-scenes battle is being waged for this legal definition, among others, by the World Health Organization (WHO).

If it is ultimately decided that CBD should be withdrawn from global drug laws or otherwise defined as a medical substance, a real revolution in the field is expected. If approved as a dietary supplement, cannabidiol will become a component consumed daily by millions of people around the world. Such a change also has broad industrial implications for the opening of new factories and job creation.

On the other hand, if it is decided that CBD is completely medical, its use will be strictly prohibited by anyone who is not a recognized pharmaceutical company holding a specific license to use, market and sell the substance after having been proven in clinical trials and regulatory records.

Cannabis Light

Pending a further announcement, CBD continues to be considered a dietary supplement until the companies selling it declare that it is a medical product. This allows the trade in CBD oils and products to continue to grow and spread around the world, especially in Europe.

In the last couple of years, CBD has taken off and along with the development of technologies to separate the molecule from the plant in the lab, medical cannabis companies around the world have started to market cannabis strains.

The feedback on the ground has been positive and very quickly the flower has become like “green oil”, which is now consumed daily by millions of people around the world as part of the daily diet.

The countries most responsible for the expansion of cannabidiol in Europe over the past two years are République tchèque and the Swiss. These two countries have long endorsed a complete non-criminalization of the use of cannabis, including THC, they form the basis of the hemp and CBD industry in Europe.

In 2015, the Czech government officially defined cannabis extracts that do not contain THC as a 'dietary supplement', which led to the explosion of the local CBD market. A striking example is the world's largest cannabis exhibition, the Cannafest, which is held annually in Prague.

Until 2015, only tea and cookies containing CBD were displayed on the festival stands. Today, those attending the event will be on display at dozens of booths selling CBD products and extracts, oils, cosmetics, sundries and whatnot.

Swiss legal cigarettes rich in CBD

But the Queen of CBD that takes to the open sea is Switzerland. In stores for a while, we could buy packets of cannabis rich in CBD sold as a “tobacco substitute”. A new company recently went even further and offers Cigarettes-CBD for sale in boxes resembling cigarette packs.

Homemade Cannabis Ointment
Cannabis Ointment

Smoking or ingesting oil for health care is not the only way to absorb CBD. Ointments for application are a success among those who suffer from psoriasis, herpes or eczema because the application of CBD to the skin alleviates the sensation of itching and pain. Hemp Seed Oil is a steroid-free version of cannabinoids that can also help repair the skin.

CBD-rich medicinal water
CBD Medicinal Water

CBD water is also one of the many innovations in the cannabis industry that are developing these days. But its "simplicity" could make it one of the most useful in providing patients with an easy way to medicate.

to read :  CBD helps prevent early onset of Alzheimer's disease

CBD in France

The rumors about CBD, its health benefits and availability in the global market, of course, have not escaped France. Thousands of French people regularly order CBD oils from abroad, mainly in Europe.

There are lawyers who interpret the Drug Ordinance in its simple sense and determine that cannabidiol is completely legal since it is not mentioned in the provisions of the law and its regulations in its clear and explicit name as for the case of THC.

Many of those who order CBD oil from overseas are parents of children with autism and / or epilepsy who have heard of the incredible effectiveness of this ingredient in relieving their seizures. children.

Confusion on the path of regulation

The rapid expansion of the CBD market, especially over the past two years, along with the uncertainty regarding the legality of cannabis components in countries around the world, sometimes leads to confusion and sometimes even deliberate deception. Along with the rare instances of companies faking and selling oils that do not contain CBD, recent research results have shown that as many as 70% of CBD products sold on the network are mislabelled.

This means that the data and the quantities of active substances there are very different from what is stated on the label.

There are cancer patients, for example, who have heard about the properties of concentrated cannabis oil RSO Oil and are looking to buy cannabis oil online. In google search, they are aimed at companies that sell 'legal cannabis oil', which therefore contains CBD but does not contain THC, which is an inseparable step in cancer treatment and therefore impossible according to the protocols of famous canadian farmer Rick Simpson it would be difficult to cure only with cbd.

CBD file: better understanding some confusions

There is also the exploitation of oil for the cosmetic industry. Companies and even individuals are setting up a production and distribution line of scented creams to be applied to the skin, to which a little seed oil is added (just a little).

The branded packaging with the cannabis flower does not hurt the pace of sales of this product. There are those who will say this is a supposed fraud, but in fact it's just another expected exploitation of the interface points between the legal and the illegal. Although not containing cannabinoids at all, the green leaf has always been considered a brand, and today more than ever.

When will it be legal?

The weed in the world of sport
The Sporty Weed

The entry of cannabidiol into the world of legal trade took an important step in October 2017 with the World Agency against Doping in Sport (WADA AMA) which announced the 2018 list in which CBD will be removed from the list. drugs that are prohibited in sports. The non-hepatic cannabis component, which has excellent anti-inflammatory and pain-relieving effects, can now become an integral part of the training menu for athletes.

CBD is worth the money and a lot

Thanks to the legalization Oregon covers several billion debts

CBD sales are expected to reach a value of $ 500 million by the end of 2017, just 200 million from 2015. The Hemp Business Journal estimates that until 2021 the US CBD market market will now reach 2.1 billion.

Variable rates

The prices of raw CBD, in kilograms, of course vary depending on the quality of the final product. Some labs produce CBD with a purity level below 90% and others reach the 99% level. The price difference between these two products is huge.

In addition to the enormous sums of money and the enormous value of the molecule, its absence of psychoactive power and its health benefits in each mode of consumption creates a new industry around cannabidiol and will allow the creation of new factories, stores. and thousands of jobs. This could happen as early as 2018, and better establish itself in France from 2019.

One of the fears in redefining "cannabidiol" as a drug concerns the transfer of rights to pharmaceutical companies. However, we can no longer turn back. But the public wants CBD and it is already available from some retailers ...

The medicinal benefits of CBD

CBD can be used to treat a variety of medical conditions. Here are some of the things CBD can do:

  • Ease the pain
  • Relieve anxiety
  • Reduce inflammation
  • Relieve psychosis
  • Stimulate the appetite
  • Reduce nausea
  • Reduce convulsions
  • Prevent degeneration of the nervous system
  • Remove muscle spasms
  • Manage blood sugar
  • Treat psoriasis
  • Inhibit the growth of cancer cells
  • Reduce the risk of blocked arteries
  • Increase bone growth
  • Kill or slow down bacterial growth

Specific disorders that CBD can treat include:

  • Schizophrenia
  • Epilepsy
  • Anxiety
  • Depression
  • Attention deficit hyperactivity disorder (ADHD)
  • Cancer
  • osteoporosis
  • Lupus
  • Diabetes
  • Obsessive-Compulsive Disorder (OCD)
  • Parkinson disease
  • Chronic Pain
  • Neuropathic pain

The essential to know

As you can see, CBD can be of great help in the fight against many chronic and debilitating conditions, but the medical community continues to gain ground. Until they produce their own dosage recommendations… In the meantime you can calculate your ideal dosage with a little experimentation and a few simple calculations. What are you waiting for ?

Weed-master

The author Weed-master

Weed media broadcaster and communications manager specializing in legal cannabis. Do you know what they say? knowledge is power. Understand the science behind cannabis medicine, while staying up to date with the latest health related research, treatments and products. Stay up to date with the latest news and ideas on legalization, laws, political movements. Discover tips, tricks and how-to guides from the most seasoned growers on the planet as well as the latest research and findings from the scientific community on the medical qualities of cannabis.