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Cannabis during spinal cord injury

Cannabis during spinal cord injury

Cannabis acts on the spinal cord as an analgesic and stimulator of the endocannabinoid system

Spinal cord trauma is trauma to the spinal cord. That is to say, the part of the central nervous system that allows communication between our body and our brain. Thus, the trauma can be caused by a fall, an accident or a failed dive ... In a serious accident cannabis can be used afterwards as an analgesic and stimulator of the endocannabinoid system, which aims to produce repair cells

Cannabis-and-spinal-cord injuries,

Spinal cord injury

Depending on the severity of the lesion, spinal cord injury can lead to motor and sensory disturbances as well as irreversible sequelae (paralysis). Paraplegia refers to paralysis of the lower limbs (legs). It is called quadriplegia when the arms and legs are affected.

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The most common symptoms are:
- Paralysis (complete if lesion of the spinal cord)
- Numbness or loss of sensation throughout the body
- Inability to control bowels or bladder
- Spasms
- Exaggerated reflexes
- Intense pain
- Tingling sensation
- Difficulty breathing

Analgesic cannabis

Cannabis can help those who have a bone marrow connection, but only to relieve strong pain in chronic situations. In a critical situation and immediately after a serious accident or surgery, analgesic (opioid) medications remain the best option. However, once the body recovers from the injury, researchers have found that cannabis improves pain management.

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In a published study Per the Journal of Pain, researchers tested cannabis in 42 patients with spinal cord injury. Each patient received either vaporized cannabis or a placebo. The cannabis used contained 2,9% or 6,7% THC. Inhaled patients were allowed 4 puffs, then the option of resuming 4 to 8 puffs three hours later. In addition, this experiment was repeated three times.

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Researchers have found that cannabis significantly improves pain management in participants. The reduction in pain is significantly improved given the psychoactive effects of THC on the endocannabinoid system.

CBD helps recovery

CBD is no exception, a study on animals examined the effects of CBD (non-psychoactive) as a pain reliever after surgically induced spinal cord injury. After an injection of 20mg / kg of CBD, 3 hours after the surgery, the CBD greatly improved the rats in terms of motor skills and mobility. Interestingly, rodents treated with CBD also had less injury throughout the tissues.

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Rodents were injected with 20 mg / kg of pure CBD before surgery, three hours after surgery. Rats treated with CBD performed significantly better than untreated rats in terms of motor skills and mobility. Interestingly, the treated CBD rodents also had less injury throughout the tissues. This finding led the authors to conclude that CBD might be effective for those in recovery from spinal cord injury.

Over-expression of cannabis

One reason cannabis can be so effective in relieving spinal pain is for the endocannabinoid system. It is the largest regulatory network in our body. It is made up of at least two different types of cell receptors (CB1 & CB2) which have a wide variety of roles. Some of them include the regulation of mood, appetite, sleep, immune function, and pain.

receptors

CB2 receptors increase cell production of the spinal cord after injury, this overexpression of endocannabinoids is favorable and manifests itself at the site of the injury. Additional research suggests that cannabinoid therapy may help suppress pain signals by activating the endocannabinoid system, all promising signs in chronic neuropathic pain.

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5 studies

1. In a 2010 study, the Department of Medicine at the University of Manitoba in Canada recruited 12 volunteers. Those suffering from lesions of the spine to test if the Nabilone (synthetic cannabinoid) could alleviate their spasticity. The results concluded that 11 out of 12 subjects showed a significant decrease in the activity of the affected muscle groups.

2. The Swiss Center for Spinal Cord Injury carried out a study in 2007 involving 25 patients with injuries to the spinal cord. THC was administered orally as an oil. THC is a safe and effective drug in the treatment of muscle spasticity.

3. In 1995, the Medical College of Georgia, Augusta, tested five quadriplegic patients. Treatment included Dronabinol. Spasticity was markedly improved in two of the five patients. However, a decrease in vigor in erratic mood states has been noted.

4. An 1982 study conducted by J. Malec and RF Harvey has compiled 43 questionnaires of cannabis users who have suffered serious spinal cord injuries. The results showed that participating 43 reported a decrease in spasticity when using cannabis.

5. In 2001, the Swiss Center for Spinal Cord Injury conducted a study of people with IBS. They all experienced overactive bladder a major side effect. 15 patients received THC orally or rectally over a 6 week period. At the end of the study, the oral group did not demonstrate a reduction in bladder activity. However, the “rectal” group showed a significant decrease in bladder activity.


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