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Scientists modified cannabis strain to kill cancer cells

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Modified form of medical cannabis can kill or inhibit cancer cells

Laboratory tests at the University of Newcastle and the Hunter Medical Research Institute have shown that a modified form of medicinal cannabis can kill or inhibit cancer cells without affecting normal cells, revealing its potential as a treatment rather than simply as a reliever medication. It is well known that the chemical compounds present in cannabis, especially the cannabidiol (CBD), are effective in treating the symptoms of many forms of cancer. It is now proven that it could potentially cure the disease by attacking cancer cells.

Cancer researcher Matt Dun of Newcastle University in Australia recently completed a three-year study showing that a specific modified strain of cannabis is destructive to certain types of cancer cells while remaining harmless to the body's own cells. human body.

according to a Press release from Newcastle University:

Laboratory tests conducted at Newcastle University and the Hunter Medical Research Institute have shown that a modified form of medicinal cannabis can kill or inhibit cancer cells without impacting normal cells, revealing its potential as a treatment rather than just a rescue medication.

The strain in question, named Eve, has been modified to contain less than 1% of the expected amount of THC, while having a very high amount of CBD.

Dun and his team worked with theAustralian Natural Therapies Group (ANTG) to develop the strain and perform the necessary tests to determine its potential as an intervention against cancer. According to Dun:

The ANTG wanted me to test it for cancer, so we used leukemia cells first and were really surprised at how sensitive they were. At the same time, cannabis did not kill normal bone marrow cells, nor normal, healthy neutrophils [white blood cells].

We then realized that a cancer screening mechanism was at play, and we have spent the last two years trying to find the answer.

The next steps will be to test the strain on other types of cancer cells and, hopefully, to convince regulators around the world to take cannabis testing seriously. Studies such as the one conducted by Dun are difficult to conduct in places where cannabis is still considered a dangerous and illegal drug, such as the United States where it remains classified as a Schedule 1 substance, next to heroin.

We've long known that cannabis is effective in treating many symptoms of cancer, but this is one of the first compelling evidence that CBD can kill cancer cells. If this research proves conclusive, we could consider an intervention for certain forms of cancer in a few decades. Best of all, low THC cannabis poses very little risk of side effects compared to almost any other promising current or experimental cancer intervention.

A three-year study is not enough to declare that the war on cancer is won. It will take peer review and a myriad of future studies to confirm the results and determine exactly why the Eve strain is effective.

EVE CANNABIS
Eve is our dominant CBD strain, exclusive to ANTG.
CBD 11-17%
THC <0,1

Dans un récent article intitulé « Can Hemp Help », publié par la revue internationale Cancers, le Dr Dun et son équipe ont également entrepris une analyse documentaire de plus de 150 articles universitaires qui examinent les avantages pour la santé, les effets secondaires et les éventuels avantages anticancéreux du CBD et du THC.

« Il existe des essais dans le monde entier qui testent des formulations de cannabis contenant du THC comme traitement contre le cancer, mais si vous suivez cette thérapie, votre qualité de vie s’en ressent », explique le Dr Dun. « Vous ne pouvez pas conduire, par exemple, et les cliniciens sont à juste titre réticents à prescrire à un enfant quelque chose qui pourrait provoquer des hallucinations ou d’autres effets secondaires.

« La variété CBD semble avoir une plus grande efficacité, une faible toxicité et moins d’effets secondaires, ce qui en fait potentiellement une thérapie complémentaire idéale à combiner avec d’autres composés anticancéreux ».

The next phase of the study is to investigate what makes cancer cells sensitive and normal cells insensitive, whether it is clinically relevant, and whether various cancers respond.

« Nous devons comprendre le mécanisme afin de trouver des moyens d’ajouter d’autres médicaments qui amplifient l’effet, et de semaine en semaine, nous obtenons de plus en plus d’indices. C’est vraiment passionnant et important si nous voulons passer à un usage thérapeutique », ajoute le Dr Dun, en soulignant que le cannabis enrichi en CBD n’est pas encore prêt à être utilisé cliniquement comme agent anticancéreux.

« Nous espérons que notre travail contribuera à réduire la stigmatisation liée à la prescription de cannabis, en particulier les variétés qui ont des effets secondaires minimes, surtout si elles sont utilisées en combinaison avec les thérapies standard actuelles et la radiothérapie. D’ici là, cependant, les gens devraient continuer à consulter leur médecin traitant habituel ».

The study was funded by ANTG and HMRI through the Sandi Rose Foundation.

  • Dr Matt Dun is from the University of Newcastle, and is doing his research in conjunction with the Hunter Medical Research Institute (HMRI) Cancer Program. HMRI is a partnership between the University of Newcastle, Hunter New England Health and the community.
Tags : CancerSearchStrain
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