Medicinal cannabis reduces nausea and vomiting caused by chemo

woman with cancer in oncology unit receiving chemotherapy treatment.

Preliminary results and first worldwide trial: significant improvement in nausea and vomiting due to chemotherapy

Researchers from the University of Sydney, Chris O'Brien Lifehouse and the NHMRC Clinical Trials Center (The National Health and Medical Research Council : main funding body for medical research in Australia) have publié preliminary results from a groundbreaking clinical trial of medicinal cannabis for cancer patients, which found it may help reduce nausea and vomiting, two common and debilitating side effects of chemotherapy.

Preliminary results from a government-funded New South Wales medical cannabis trial sponsored by the University of Sydney show significant improvement in nausea and vomiting from chemotherapy.

The CannabisCINV study, funded by the $ 21 million invested by the Government of New South Wales to explore the therapeutic potential of medicinal cannabis, includes ground-breaking clinical trials around the world. The largest medical cannabis trial in the world at the time of its launch is a collaboration with leading New South Wales cancer centers.

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The results published in Annals of Oncology revealed a significant improvement in the control of nausea and vomiting induced by chemotherapy. A quarter of patients taking medicinal cannabis did not experience vomiting or nausea, compared with 14% of people who took a placebo.

These encouraging results indicate that medicinal cannabis can help improve the quality of life of patients undergoing chemotherapy.

nausea, chemotherapy
Former New South Wales Premier Mike Baird, Deputy Health Minister Pru ​​Goward and Associate Professor Peter Grimison

The pilot phase of the study lasted two and a half years, with 81 participants enrolled. To be included in the study, patients had to have experienced nausea and vomiting during chemotherapy in the past despite taking nausea-preventing drugs.

"Nausea and vomiting are among the most distressing and dreaded consequences of chemotherapy," said lead investigator Peter Grimison, associate professor at the University of Sydney School of Medicine and medical oncologist at Chris O'Brien Lifehouse.

These encouraging results indicate that medicinal cannabis can help improve the quality of life of patients undergoing chemotherapy.

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Side effects such as sedation, dizziness, and drowsiness have been rated as moderate to severe in about a third of people using medicinal cannabis, but they are considered manageable.

"The trial will now move into a larger phase to determine with much more certainty the effectiveness of medicinal cannabis and whether to consider its use in routine cancer care," said Professor Grimison, of the Faculty of Medicine and Health.

The next phase of the trial is underway and will recruit 170 additional people.

The trial is sponsored by the University of Sydney. Medicinal cannabis is supplied by Tilray, a GMP certified medical cannabis producer.

Tags : Cancerchemotherapy

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