Health organizations seek opinions and comments on 16 drug substances. The Convention on Psychotropic Substances will determine the future perception of cannabis and its derivatives.
The Food and Drug Administration (FDA) is asking interested people to provide feedback on the abuse risks, actual abuse, medical utility, trafficking, and impact of 16 medicinal substances for medical use. These comments will be taken into account in preparing a US response to the World Health Organization (WHO). This concerning the risk of abuse and the diversion of these so-called “drugs”… The cannabis plant is unfortunately part of the list. Indeed, the plant will soon be subjected to a critical analysis by experts, and the public ...
Convention on Psychotropic Substances
WHO will use these informations to determine whether to recommend the imposition of certain international restrictions on the 16 psychotropic substances in the international schedule. Among the substances, we find Cyclopropyl Fentanyl, Methoxyacetyl Fentanyl, Fluoro Butyrfentanyl. As well as the Tramadol, Pregabalin and other really dangerous substances. But, cannabis will also be part of the list, in its natural form, in extraction, or others ...
Call for comments
This notice for comment is required by the Controlled Drugs and Substances Act (the CSA). In addition, the United States is an integral part of 1971 Convention on psychotropic substances… The Convention on psychotropic drugs refers to theWHO, which has information on a substance which it believes may require international control or modification. Ultimately, it will inform the Secretary-General of the United Nations (ONU) and provide him with information to support his opinion ...
Cannabis under debate
Cannabis is a plant known by the organic names Cannabis sativa or Cannabis indica. It is a complex plant substance containing multiple cannabinoids and other compounds, including the cannabinoid THC (psychoactive), and other structurally similar compounds. Cannabinoids are defined as having activity at cannabinoid receptors 1 and 2 (CB1 and CB2 respectively). In addition, CB1 receptor agonists are widely recognized to modulate motor coordination, memory processing, pain, and inflammation. In addition, the anxiolytic effects of these two cannabinoids are also recognized.
(-) - trans-delta-9-THC (also known as dronabinol), the only pure, synthetically derived stereoisomer, is the active ingredient in two drugs approved in the United States:
- MARINOL (dronabinol) in capsules (and generics)
- SYNDROS (dronabinol) in oral solution.
- MARINOL under Annex III
- SYNDROS under Schedule II of the CSA.
MARINOL and SYNDROS are prescribed for the treatment of anorexia associated with weight loss in patients with acquired immunodeficiency syndrome (AIDS). In addition, they are also prescribed for nausea and vomiting associated with cancer chemotherapy. Note that these synthetics are often useful in patients who do not respond adequately to traditional treatment.
CBD is another cannabinoid constituent of the cannabis plant. In the United States, a product containing CBD, the oral solution Epidiolex, has received FDA approval for the treatment of seizures associated with two rare and severe forms of epilepsy, Lennox-Gastaut syndrome and Dravet syndrome, in patients 2 years of age and older.
However, the recent decision taken on September 28, 2018 by the MFA regarding Epidiolex and all future similar formulations of CBD that become drugs approved by the FDA (Schedule V of the CSA). The Convention on Biological Diversity does not appear expressly in the tables of the international drug control conventions of 1961, 1971 or 1988 ...
Cannabis plant and derivatives
The 40th meeting (2018) of theECDD, critically reviewed CBD. Preliminary examinations were done on the plant and cannabis resin. Concerning also, extracts and tinctures, THC and isomers of THC. In the end, it is recommended that preparations considered to be pure CBD should not be included in the annexes to the International Drug Conventions.
But, the cannabis plant, will be subjected to a more than critical examination… The public being invited to offer its comments… THC and the isomers of THC are always in the crosshairs of the said critics. internationally… However, the recent legalization in Canada could raise awareness of the debate. A declassification of Annex 1 is awaited, with respect to the cannabis plant as a whole. Indeed, the majority of the public and the scientific community, no longer judges its substances as being drugs ... For example, a comment recently received, indicates to us that:
Cannabis, when consumed by responsible adults, can be a slightly healthier alternative to alcohol and cigarettes. It should be legal for recreational and medical purposes at the federal level. It can be taxed and regulated. A lot of states have legalized already, so we might as well legalize at the federal level. Cannabis is not only used to treat serious illnesses, it is also used over the counter.