The consumption of cannabinoids is associated with a decrease in constipation

Study says people who use cannabis are less likely to suffer from constipation

In survey whose results have been published in The American Journal of Gastroenterologyn, Dr. Kyle Staller of the Gastroenterology Division at Massachusetts General Hospital and his colleagues wrote that cannabis use could potentially alter the gastrointestinal system.

"Current evidence suggests that cannabinoids slow colonic transit through actions on the CB1 receptor," they wrote. However, a recent clinical trial reported that hemp seed pills improved symptoms of constipation in patients with functional constipation, suggesting that the summative effect of separated cannabinoids in the cannabis plant could have a unique effect on intestinal motility. "

A five-year study of data

To explore the effects on bowel function, the researchers selected adults (aged 20 to 59 years) who completed a questionnaire on drugs and intestinal health at the US National Health and Nutrition Survey. during a period of 6 years, from 2005 to 2010. They estimated the likelihood of constipation or diarrhea depending on the state of cannabis use.

Overall, Staller and colleagues found that the prevalence of constipation was lower among those who reported recent marijuana use than those who used it longer or who did not use marijuana. never consumed. Recent marijuana use has also been associated with reduced risk of constipation.

This decline persisted after adjusting for age and demographic factors, co-morbidities, substance use, constipating medications, general health status, physical activity, and emotional and diet disorders. food. There was no connection between recent weed consumption and diarrhea.

New studies to refine the results

"Our analysis is the first clinical study linking cannabis and intestinal function in humans based on a sample of the population, providing important information on the overall effects of different components of cannabis on constipation," wrote Staller and his colleagues. "Due to the prevalence of constipation and the increasing availability of cannabis for recreational and medicinal purposes, further studies are needed to determine how the use of cannabis, different strains and the frequency of consumption exert their apparent effects. on constipation. "

Tags : cannabinoidsConsumptionEndocannabinoid system