CBD reduces blood pressure, and the cardiovascular response to stress
Epidemiological studies have shown a positive relationship between long-term stress and the development of cardiovascular disease. CBD (canabidiol) is currently the subject of much research due to its therapeutic potential. And according to the latest clinical trial data published online in Journal of Clinical Investigation: Oral administration of CBD is positively associated with reduced blood pressure in healthy volunteers.
CBD in disorders of the cardiovascular system
Factors such as social isolation, socioeconomic status, depression, stressful and professional life, and anxiety are associated with an increased risk for the development and accelerated progression of cardiovascular disease. The current European directives on the prevention of cardiovascular diseases have emphasized the importance of tackling these factors. Thus, mental stress induces myocardial ischemia in patients with coronary artery disease.
Cannabinoids (CBs) are compounds that bind to CBD receptors. They are structurally similar to compounds that bind to CB receptors. The other major phytocanabinoid is cannabidiol (CBD), which does not have psychoactive properties. In addition, canabidiol has been shown to have anti-inflammatory, anticonvulsant, antioxidant, anxiolytic, anti-nausea and antipsychotic properties. It is even found to be therapeutic in cases of stroke. A number of pre-clinical studies have also proven beneficial effects of CBD in a range of cardiovascular system disorders.
The researchers from the University of Nottingham evaluated the effects of a single oral dose of 600 mg of CBD extract compared to placebo in nine male subjects. They concluded that administration of cannabidiol reduced systolic blood pressure and vascular volume. That is, the amount of blood pumped by the left ventricle of the heart in one contraction. An increased heart rate has been observed following administration of CBD. But no adverse events were reported by participants during or after the study sessions. The authors concluded:
“Our data shows that a single dose of CBD reduces resting blood pressure. And in the blood pressure response to stress, especially cold stress. "-" This may reflect the anxiolytic and analgesic effects of CBD, as well as any potential direct cardiovascular effects ... Further research is also needed to determine if CBD has a role in the treatment of cardiovascular disorders such as hypertension. "
Animal studies also show that canabidiol modulates the cardiovascular stress response Thus, CBD decreases the cardiovascular stress response after the administration of a single dose of CBD (600 mg). This with the assumption that blood pressure would be reduced by CBD. Thus, cannabis has multiple desirable effects on the cardiovascular system.