- 1. CBG (cannabigerol), a new ready-to-use cannabinoid, joins the 1 class of cannabinoids
CBG (cannabigerol), a new ready-to-use cannabinoid, joins the 1 class of cannabinoids
There are 130 types of cannabinoids, useful and listed in marijuana. THC and CBD have been in the spotlight for a few then, but there are 83 others that are not inactive, and which can also greatly improve your health, including CBG (cannabigerol) finally ready to use.
One of those little-known cannabinoids that will soon make a splash is cannabigerol (CBG). Cannabigerol is an active compound in cannabis believed to have anti-bacterial properties. CBG has also been proven as inhibiting the capture of GABA. This causes a relaxation effect normally associated with CBD.
Cannabigerol (CBG) is a cannabinoid non-psychoactive which plays an important role in the biochemistry of cannabis. GBC acts as a chemical precursor to other cannabinoids like THC and CBD. This Conversion usually takes place 6-8 weeks in the flowering cycle. CBG is only present in trace amounts in most strains of cannabis, but certain strains of hemp are specifically cultivated to generate higher yields of this cannabinoid. But, most of the strains found on the market only contain about 1% of this cannabinoid.
However, CBG has prompted further research into cannabinoids. These contemplate possible much broader implications. Today two different medical companies are ready to deliver their CBG-based product, completing a new database on the properties of Cannabigerol.
CBG the neuroprotective cannabinoid
A survey reveals that CBG is strongly active in repairing protective brain cells. In 2015, researchers from the Department of Biochemistry and Molecular Biology at the Complutense University of Madrid in Spain, found that CBG has neuroprotective properties.
Since CBG is highly active, it improves motor deficits and preserves neurons. But, the potent neuroprotective cannabigerol, is also an anti-inflammatory agent. This is confirmed by another study of Journal of Neuroimmune Pharmacology, which found its effect on multiple sclerosis.
Relieves neuropathic pain
CBG therefore shows promise in relieving neuropathic pain. A patent issued by Otsuka Pharmaceutical et GW Pharma tells us that cannabigerol along with other cannabinoids (CBC, CBDV and THCV) help alleviate symptoms of neuropathic pain (in mice). CBG helped these mice recover from pain caused by surgically induced nerve damage.
Namely that neuropathic pain, is generally refractory to opioids ... Lower doses were necessary to relieve pain in these mice. Cannabigerol is therefore effective in the treatment of neuropathic pain. All of these studies show that CBG remains very promising, whether used alone or in combination with other cannabinoids.
Studying CBG and other Cannabinoids is essential to understanding the overall health effects of cannabis. The entourage effect, this synergy that THC, CBD, as well as the main cannabinoids and terpenes used for health, interact with our body, and also separately with other components.
CBG can also reduce intraocular pressure in glaucoma, and may even be effective in treating nausea and vomiting. CBG has multiple anti-inflammatory effects that could be helpful in bowel disease, just like other cannabinoids would. They are all derived naturally from the cannabis plant. And to be more precise, this same cannabis plant is ready just like CBG for medical use, on a large scale ...
CBG-A: The mother of cannabinoids
The "g" in CBG-A should be considered informally to mean "genesis". This unique cannabinoid is the chemical source for many more, including all of those mentioned above. In fact, cannabis wouldn't have any euphoric value and would have very little medicinal value without these particular cannabinoids.
CBG-A is a special acid precursor that gives rise to therapeutic cannabinoids for a wide range of diseases and conditions, from arthritis to Crohn's disease and cancer. In fact, a study conducted in Israel in 2013 found that cannabis puts Crohn's disease in complete remission in about 50% of cases.
In the world of botany and biology, chemicals create chemicals. Molecules transform under certain conditions, such as heat, light and oxidation, to become slightly modified cousins of themselves. Although their new chemical structure may be only slightly different, it is often enough to cause a dramatic change in medicinal efficacy in patients or a different psychoactive effect in adult users.
Acid precursors are slightly different versions of cannabinoids which, under the right conditions, transform into the familiar molecules used to treat or provide euphoria to millions of patients. Take THC, for example. It is the most common and abundant cannabinoid (by volume) in most strains of cannabis. It is created by its acid precursor, THC-A (sometimes called THCA or THCa).
When heat is applied to THC-A, for example from the flame of a lighter during smoking or from the stream of hot air produced by a vaporizer, this precursor causes a cluster of carbon dioxide (COO ) to become everyone's favorite molecule, THC (this process is called decarboxylation because it decouples one carbon and two oxygenes).
Likewise, CBD, CBC, and CBG are also created by acidic precursors: CBD-A, CBC-A, and CBG-A, respectively. All these acid precursors are themselves derived from CBG-A. In this regard, CBG-A is the mother of many critical and medicinal cannabinoids. This is because CBG-A is indirectly responsible for a wide range of positive medical therapies, including the following:
- Anti-cancer: THC-A, CBD-A, THC, CBD, CBC, CBC, CBG
- Analgesic (Analgesic): CBG-A, THC, CBD, CBC, CBC, CBG
- Anti-inflammatory: THC-A, CBD-A, CBC-A, THC, CBD, CBC, CBN-A, CBN-A, CBN
- Anti-spasmodic: THC-A, THC, THC, CBD
- Appetite stimulant: THC
- Appetite suppressant: THCV
- Bone Stimulant: THC-A, THCV, CBD, CBDV, CBC, CBC, CBG
- Bronchodilator: THC
- Sleep aids (anti-insomnia): CBD, CBC, CBN
Two companies involved
Canada-based Medical Marijuana Corporation Whistler has announced plans to release a new cannabis extract from a plant with a "unique phenotype", which is both high in CBG and THC. This is somewhat unusual, given that CBG is usually found in higher amounts in hemp, than rather in the flowers (buds, buds) of marijuana.
This concentrate will be distributed to patients registered with WWMC. This in the hope of learning more about the therapeutic effects of CBG. Especially when this cannabinoide is consumed in the company of THC.
"We are extremely pleased to offer CBG to our patients. And we hope it will expand a lot of conditions "WWMC
Basic research has indicated that CBG has a variety of effects in a cell culture and on (laboratory) animals. It acts as an anti-inflammatory, analgesic and antifungal. CBG is currently under investigation for possible treatment for many disorders. It will be found in cancer treatment, glaucoma, and inflammatory bowel disease. CBG would also seem useful for neurovegetative diseases such as Huntington's disease.
Earlier this year, another company launched a product based on CBG. This is the company Axim Biotechnologies based in the Netherlands. AX-1602 is prescribed for clinical test . This one to treat skin diseases, such as psoriasis and eczema.
Axim claims that CBG has shown tremendous efficacy as an anti-inflammatory. It demonstrates several health benefits such as the ability to "slow down" the proliferation of tumor cells in vitro and in vivo.
The chemistry of cannabis can become complex and confusing for laymen. However, a small amount of knowledge about the role of a few dominant cannabinoids may be helpful in understanding the herbal therapy and why it is considered by many to be such a potent drug that is almost completely devoid of addiction or harmful side effects.