Potential of CBD in the treatment of ischemic stroke
Ischemic stroke is linked to a blocked artery in the brain. In an ischemic stroke or cerebral infarction, a clot blocks the cerebral circulation. Damage is caused to the brain by the interruption of its blood supply .; there are over 200.000 cases of ischemic stroke in the United States… According to a new Japanese study, cannabidiol (CBD) may provide a potential and significant option for the treatment of ischemic stroke.
Ischemic cerebrovascular accident (stroke)
An ischemic stroke (CVA) is a consequence of the lack of oxygen in a part of the brain. It can be, among many causes, the consequence of a thrombosis (occlusion) of the internal carotid artery. Or an embolism (migration of a clot or debris of fatty deposits) cerebral.
Stroke can be transient (transient ischemic attack) if recovery occurs within a few hours. Otherwise we say that the stroke is established. Thus, the recovery is then more or less complete over several weeks. Sometimes the after-effects are important and definitive ...
In 80% of cases, stroke is caused by a drop in blood supply due to an obstacle inside a cerebral artery. We then speak of ischemic accidents.
There are various well-known risk factors, some of which can be avoided by effective prevention: Age. Thus, more than half of strokes occur in people aged 75 and over. But a quarter of those under 65 are susceptible to stroke.
- Certain heart diseases (abnormal heart valve, insufficiency or arrhythmia)
- High blood pressure which is a major risk factor.
- A first stroke or TIA. The transient ischemic attack indicates that the risk of stroke is important.
- Diabetes. This chronic disease, characterized by an excess of sugar in the blood, contributes to fatty deposits
- Tobacco use: Stopping smoking halves the risk of stroke.
- The consumption of alcohol which also acts on the value of the blood pressure.
CBD therapeutic potential
It is well known that delta⁸-THC and other CB₁ receptor agonist cannabinoids are neuroprotective during global and focal ischemic injury. In addition to the CB récepteur receptor agonists, cannabis contains specifically active and therapeutic components which are directly and independently linked to the CB₁ receptors, CBD being the main actor.
Over the past five years, an increasing number of publications have focused on the discovery of the anti-inflammatory, anti-oxidant, and neuroprotective effects of CBD. Cannabinol (CBD) exerts positive pharmacological effects in ischemic stroke and other chronic diseases, including Parkinson's disease, Alzheimer's disease, and rheumatoid arthritis etc ...
Which is confirmed by the study Japanese published in the journal Pharmaceuticals “The cerebroprotective action of CBD is independently linked to CB₁, the action is long-lasting, and possesses powerful antioxidant activity. In addition, the researchers add that "the treatment with CBD does not lead to drug dependence". According to one other study published last year in the Journal of Neurochemistry, activating cannabinoid receptors is something cannabis does naturally. Indeed, this is what helps protect neurons and considerably improves motor recovery during an ischemic stroke.
In other words, cannabinoids "lessen damage and improve memory retention when memory is damaged by stroke." Indeed, CBD appears to be a viable treatment option for people with ischemic strokes.