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Cannabis against breast cancer

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Beneficial role of CBDA and CBD (hemp extract) in the case of breast cancer

Breast cancer is the second most common cancer in women; one in ten will be affected at some point. There are a variety of very effective chemical, radiological and surgical treatment options. But they are not particularly pleasant. In addition, some tumors are resistant and prone to relapse. As remarkable as it may sound, there is a growing body of reliable evidence suggesting that the CBDA and CBD in hemp can slow down, hinder tumor growth, and significantly in the case of breast cancer.

Cannabis a breast cancer therapy

according to the National Cancer Institute (National Cancer Institute), breast cancer is one of the most common types of cancer in the United States, The nonprofit Breastcancer.org reports that about 1 in 8 women in the United States (12%) will develop invasive breast cancer at some point in her life. Note that men and women can also develop breast cancer.

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246 660 new cases of breast cancer diagnosed this year in the United States.

Role of CBDA in breast cancer

In the case of breast cancer, a new Japanese study shows that cannabidiolic acid (CBDA) effectively inhibits the spread of breast cancer cells, by downregulating a proto-oncogene called c-fos.

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Cannabidiolic acid (CBDA) prevents the spread of breast cancer cells, according to the results of a new Japanese study, published in the Journal of Natural Medicines. CBDA, the precursor of cannabidiol acid (CBD), is a non-psychoactive compound in cannabis plants. When CBDA is heated and smoked, by vaporization, or decarboxylation, it is converted into CBD.

In the study, the researchers, led by Shuso Takeda of Hokuriku University, found that CBDA inhibited the migration of cancer cells responsible for the invasive spread of breast cancer.

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“Researchers' identified CBDA as an inhibitor of MDA-MB-231 cell migration, a cell line responsible biologically for human breast cancer, due to its highly aggressive nature. "

The 2012 study by Takeda was the first to demonstrate that CBDA effectively inhibits the spread of highly invasive breast cancer cells in humans. In 2014, Takeda and his team found that CBDA was able to suppress breast cancer cells by inhibiting cyclooxygenase-2 (COX-2), an enzyme known to be involved in inflammatory processes and in metastasis of cancer cells.

BREAST CANCER

Selective regulation of c-fos

Takeda found similar results in this recent study. However, he and his team too may have identified the molecular mechanism responsible for the downregulation induced by cyclooxygenase (COX-2). Takeda and his research team “describe a possible mechanism by which CBDA abrogates the expression of cyclooxygenase-2 (COX-2) through selective (down) regulation of c-fos (proto- oncogene), a component of the activator protein-1 (AP-1), and a transcription factor for upregulation of the cyclooxygenase-2 (COX-2) gene. Overexpression of the proto-oncogene c-fos is linked to a wide variety of cancers.

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An oncogene is a gene whose expression promotes the onset of cancer; manifested here as a lung tumor

CBD & CBDA effective against many cancers

Previous research suggests that other cannabinoids found in cannabis also have anti-carcinogenic effectss. Several on CBD prove its effectiveness in inhibiting the progression of breast cancer, lung cancer, prostate cancer and colon cancer. Cannabis is also very beneficial in mediating pain. He fights against nausea, fatigue, weight loss, sleep disturbances, constipation, mood disturbances, and itching associated with chemotherapy treatments.

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Because of its effectiveness, almost all of the United States that has passed medical marijuana laws has included cancer on their list of approved conditions for a medical cannabis prescription. CBD and CBDA, derived from industrial hemp (instead of medical marijuana) are non-psychoactive, and therefore legal.

Tags : Medical research and scientific advances
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The author weed master

Weed media broadcaster and communications manager specializing in legal cannabis. Do you know what they say? knowledge is power. Understand the science behind cannabis medicine, while staying up to date with the latest health related research, treatments and products. Stay up to date with the latest news and ideas on legalization, laws, political movements. Discover tips, tricks and how-to guides from the most seasoned growers on the planet as well as the latest research and findings from the scientific community on the medical qualities of cannabis.

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