CBD can provide an alternative treatment route for a variety of skin diseases, particularly atopic dermatitis (AD)
Cannabidiol (CBD) is attracting great attention for its therapeutic potential against various pathologies, including skin diseases. Topical hemp containing CBD is one of the most accessible entry points, creams and lotions are appearing everywhere in specialty shops. Practically every day, a new therapeutic or drug application is discovered for one of these cannabinoids.
What does the research say?
Cannabinoids have anti-inflammatory, antimicrobial and anti-itch properties, but recently, serious research has been published to understand the underlying physiological effects.
In the history of research to date on dermatological diseases and the cannabis plant, CBD oil from hemp can help fight skin conditions including eczema. It is also found in beauty products, from body care to make-up. A new use of this molecule would also cure acne. Research has repeatedly proven that some cannabinoids could be used as a treatment against Psoriasis. As another example, many features of Alzheimer's disease contribute to itching, including dryness of the skin, release of histamine, and sensory nerve fibers. Cannabinoids have a powerful anti-itch effect.
How does it work?
One possible explanation is that the cannabinoids THC and CBD function as immunosuppressants. Additionally, CBD is an excellent anti-inflammatory, so it could also relieve the symptoms of skin diseases, especially atopic dermatitis.
The skin contains receptors that interact with cannabinoids and may reduce symptoms. These effects occur through a range of interactions between phytocannabinoids and our endogenous cannabinoid system.
Cannabidiol induces antioxidant pathways in keratinocyte : these are the cells constituting 90% of the superficial layer of the skin (epidermis) and integuments (nails, hair, hairs, feathers, scales). In other words, topical CBD increases the levels of keratins associated with overgrowth and wound repair in the skin.
The future of cannabis creams for eczema?
So far, there is no cure for these diseases. It is possible to treat them with steroids, but they are not always effective.
The effect of cannabinoids in patients with eczema has already started to be demonstrated. Fortunately, there are several routes of administration. There are topical ointments, which in addition to reducing symptoms with cannabis, help hydrate the skin.