The Delta 3 Carene: terpene that promotes bone health


Delta terpenes 3 hull fights inflammation repairs damaged, diseased bones and promotes concentration

Among the 200 varieties of aromatic molecules called terpenes manifested in cannabis, the delta 3 carene also called alpha-carene is one of the best terpenes to repair bones and promote their growth.

From the 1960 years, researchers began to note the medicinal efficacy of phytochemicals from plants such as cannabis. Among these chemical compounds are cannabinoids. The best known examples are THC, CBD, terpenes such as 3 carene delta, myrcene, pinene and flavonoids.

At first, it was believed that terpenes simply transmitted an intense aroma to the plant. From an evolutionary point of view, these molecules serve to protect pests and predators.

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Delta 3 Carene

Particularity of the Delta 3 Carene

The Delta 3 hull emits a sweet and spicy fragrance composed of citrus, cypress, pine and wood. It is produced from plants other than cannabis, including rosemary, pine and cedar. Delta 3 is used by the cosmetics industry as a perfume and as an insect repellent at the industrial level, it is a natural constituent of turpentine.

With regard to medicinal efficacy, the 3 Carene Delta provides significant qualities to combat systemic inflammation, repair damaged and diseased bones. It is also said to promote mental concentration. Cannabis-rich strains of cannabis have proven to be beneficial for people with arthritis, fibromyalgia and even the disease Alzheimer. This terpene is found most often in cannabis strains such as: AK-47, Arjan's Ultra Haze, Jack Herer, OG Kush, and Super Lemon Haze.

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Beyond bone repair, the 3 Hull Delta is unique among terpenes because of its ability to extract liquids (one of its main applications in the cosmetics industry). This drying effect makes the 3 delta hulls a candidate for use as a antihistamine and in products targeting excessive menstruation or mucus production. This quality is also responsible for anecdotal reports of dryness of the mouth (cotton mouth) and red eyes in smokers.

What does the research say

Research has revealed the medicinal efficacy of terpenes such as the 3 carene delta since the 1980 years. A study of 1989 entitled "Comparative Study of Different Essential Oils of Bupleurum Gibraltaricum Lamarck", Published in the journal Europe PMC, has studied the anti-inflammatory properties of the 3 carene delta. concluding that "the essential oil of the population of the Cázulas Mountains was the most active against acute inflammation because of its high delta 3-carene content".

Bupleurum gibraltaricum

The comparative study was carried out on the essential oil extracted from the fruiting apex of Bupleurum gibraltaricum harvested in different areas of the province of Granada, namely the Cázulas Mountains, the Balcón de Canales and the Quéntar reservoir. The three essential oils had a very similar chemical composition, consisting mainly of monoterpene hydrocarbons (delta 3-carene and alpha-pinene). When determining the anti-inflammatory activity against both acute inflammation (carrageenan-induced plantar edema) and subchronic inflammation (granuloma technique), quantitative differences appeared: the essential oil of the Cázulas mountains was more effective against acute inflammation due to its high content of delta-3-carene, while the essential oil of the Quéntar Reservoir, B. gibraltaricum was more effective against inflammation caused by granuloma.

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A study of 2007 entitled "Low Concentration of 3-carene Stimulates the Differentiation of Mouse Osteoblastic MC3T3-E1 Subclone 4 CellsPublished in the journal Phytotherapy Research has tested 89 natural compounds for their ability to maintain bone repair, treat bone diseases and promote overall bone health.

In this study, the anabolic activities of 89 natural compounds were evaluated by measuring the amount of newly synthesized calcium in the process of differentiation of mouse osteoblastic MC4T3-E3 subclone 1 cells. Among these compounds, a low concentration (up to 5 μ m) of 3-carene, bicyclic monoterpene in essential oils extracted from pines, significantly stimulates the activity and expression of alkaline phosphatase, a phase marker early osteoblastic differentiation, the day 9. has significantly promoted calcium induction in a dose-dependent manner. The stimulating effect of 3-carene on mineralization may be associated with its potential to induce expression / activation of mitogen-activated protein kinase and gene transcription levels related to osteoblast mineralization, such as osteopontin and type I collagen. Further studies are needed to determine the precise mechanism, but the anabolic activity of 3-carene in bone metabolism suggests that the use of natural additives in the diet, including including essential oils, could have a beneficial effect on bone health.

The researchers in the study concluded, "More studies are needed to determine the precise mechanism, but the anabolic activity of 3-carene in bone metabolism suggests that the use of natural additives in the diet, including including essential oils, could have a beneficial effect on bone health ".

Tags : Anti-inflammatoryterpene