Pharmaceutical company tackles tequila bacteria to produce THC
Farmako, a cannabis pharmaceutical company based in Frankfurt, Germany, recently filed a patent for a gene editing process that turns tequila bacteria into biosynthetic cannabinoids, reports the magazine. Futurism.
This bacteria spits THC instead of tequila.
The genetically modified bacterium is called Zymomonas cannabinoidis, a modified version of the Zymomonas mobilis gene, which is used to produce tequila. By feeding on sugar, the bacterium produces biosynthetic cannabinoids such as tetrahydrocannabinol (THC) and "more than 180 known cannabinoids," according to a press release. The process could make cannabinoid production "a thousand times cheaper".
as we have reported in Februaryseveral organizations are working to develop more cost-effective ways of producing THC, CBD and other cannabinoids. For example, scientists have uncovered a process by which a sugar present in brewer's yeast can be transformed into cannabinoid compounds.
THC lime salt: Yeast VS bacteria
The process that could make the production of cannabinoids such as tetrahydrocannabinol, better known as THC, a thousand times cheaper, according to the company.
Last month, researchers at the University of California managed to produce cannabinoid components from yeast in the laboratory. Producing cannabinoids without growing marijuana could be of interest to pharmaceutical companies wanting to add these ingredients to their products in the future. Farmako says his new technique represents the first production of cannabinoids by biosynthesis without the use of yeast.
Farmako argues that the use of bacteria instead of yeasts could make the process of cannabinoid extraction much easier on an industrial scale, since cannabinoids and yeast cells must be broken down after synthesis.
The bacteria, on the other hand, "releases the cannabinoids produced directly into the surrounding environment," said Patrick Schmitt, co-founder of Farmako.
High sugar level
To switch from one cannabinoid to another, "just exchange a single gene," says Schmitt, co-founder of Farmako. This prevents the bacteria from producing alcohol.
The genetic version of the bacteria used to produce tequila can not only produce cannabinoids by feeding on sugar, but it also produces a massive range of "more than 180 known cannabinoids". "This allows continuous production without interruption."