24 benefits of CBD (Cannabidiol) oil in medicine
Cannabidiol (CBD) is a powerful natural chemical compound that plays an important role in treating various pathologies. This cannabinoid does not cause a psychoactive side effect, as could THC (another cannabinoid also present in the cannabis plant). There are many benefits of using CBD for our health, both physically and psychically. CBD can be found in various forms, including oil, the most popular thanks to its rapid absorption and effective action.
What is CBD?
Cannabidiol (CBD) is one of the most 113 cannabinoids, natural compounds found in Cannabis sativa - the cannabis plant, or hemp. The CBD and THC (delta-9-tetrahydrocannabinol) are the 2 main active compounds found in the cannabis plant and the most recognized and studied.
However, Cannabidiol (CBD) is emerging as a powerful supplement for human as well as animal health. It is recognized as a safe anti-inflammatory that can help against several previously incurable diseases. CBD oil can help fight cancer and irritable bowel disease, improve symptoms of schizophrenia, relieve anxiety, and help you sleep better. The human body seems prewired for Cannabidiol. Thus, CBD demonstrates promising benefits for a variety of conditions. Here are the 23 benefits of CBD:
CBD has promising properties against cancer. Although THC has similar anticancer effects, its use in high doses causes too many psychoactive side effects.
Overall, CBD is safe, and has strong antitumor effects. It could be used to improve the effectiveness of standard treatments, or even potentially as anticancer substance himself. CBD prevented the growth of cancer cells and killed cancer cervix, leukemia, lung, thyroid and colon cancer in the cells.
The CBD is promising in the fight against breast cancer and prostate, because it directly reduces tumors, relieves pain and can improve the effectiveness of conventional drugs. In addition, CBD also reduces the growth and invasion of human brain cancer cells (glioma). This makes it possible to hope to fight this type of cancer difficult to treat and mortal.
CBD decreases energy production in cancers, triggering their death. It makes cancer cells kill themselves (apoptosis), stopping at once growth and spread cancer.
Inflammation and autoimmunity
CBD is a very promising remedy for a variety of inflammatory and pain-related conditions. Cannabidiol acts on the cannabinoid system of the body to reduce inflammation, balance the immune system and protect against oxidative stress.
This internal cannabinoid system can become unbalanced in autoimmune diseases and inflammation, which scientists had no idea two decades ago. CBD acts on immune cells to trigger a host of anti-inflammatory and antioxidant reactions.
CBD protects the cells of the brain. It has helped to counteract the effects of toxic substances and oxidative stress in brain cells, which would be important to recover from a stroke or other forms of brain damage.
Because of its anti-inflammatory and antioxidant properties, CBD is promising to help people with amyotrophic lateral sclerosis (SLA) and perhaps extend their lives. In addition, he was able to reverse poor cognitive function in animals with Alzheimer's disease and Parkinson's disease. CBD protected against brain damage (reducing beta-amyloid toxicity) and reduces blood flow in animals.
Overall, it appears that CBD can protect the brain from damage and inflammation, but it does not have a beneficial effect on all the movement problems that result from brain damage.
Relieves symptoms of multiple sclerosis
Cannabinoids can relieve the symptoms of multiple sclerosis (SEP). In survey (open) conducted with 66 patients with MS and chronic pain, a combination of CBD and THC reduced pain over a period of 2 years. The patients themselves determined the dosage, taking as much as they thought necessary to relieve the pain.
A combination of CBD and THC contributes to muscle contraction, pain, sleep disturbances and bladder control. However, it has been reported that lower doses have had a smaller effect, so some MS patients may need higher doses for relief.
Beneficial effects in case of schizophrenia
CBD is a potential treatment for psychosis. One study, found that when CBD is effective for relieving symptoms of schizophrenia. Including in case of social withdrawal, or when the patient is dulled by emotional expressions. The improvement was correlated with the blood levels of anandamide, which is our internal cannabinoid.
Studies suggest that CBD has effects similar to those of atypical antipsychotics, but with fewer side effects.
Helps treat epileptic seizures
CBD could be a promising therapy against epilepsy resistant to treatment. Children treated at the CBD also benefited from increased alertness, a better mood and a better sleep. (Somnolence and fatigue were side effects.)
After 3 month of treatment with 98% oil-based purified CBD extract, 39% of children with treatment-resistant epilepsy had a reduction more than 50% of seizures. After receiving 200 at 300 mg / day of cannabidiol for up to 4,5 months - 7 patients on 8 with generalized secondary epilepsy and resistant to antiepileptic drugs had their improve state.
Studies have shown that CBD significantly reducesanxiety and discomfort caused by speaking in public at a dose of 600 mg. CBD has also reduced the anxiety caused by the use of THC.
The researchers suggest that it could be effective for panic disorder, Obsessive Compulsive Disorder and post-traumatic stress disorder.
Studies suggest that cannabinoids may be a new class of drugs for the treatment of chronic pain.
We have receptors for cannabinoids throughout the body, but the first type - CB1 - is very dense in the pathways of pain in the brain, spine and nerves. The second type - CB2 - is more important for the immune system, but is also involved in inflammation. By gently acting on both routes, our internal cannabinoids and CBD can balance the pain and inflammation.
Beneficial for rheumatoid arthritis
Because of his anti-inflammatory effect, CBD can relieve joint pain and swelling - and decrease joint destruction and disease progression.
The administration of CBD protected the joints from severe damage, decreased progression and produced an improvement in arthritis. les chiens.
Relieves nausea and increases appetite
CBD oil helps reduce food sensitivities. And, according to the National Cancer Institute, CBD increases appetite by binding to cannabinoid receptors in the body.
For cancer patients, a balanced combination of THC and CBD may be the best option to increase appetite and reduce nausea. The "high" of THC is usually too strong, and CBD can help reduce these psychotropic effects, but does not reduce appetite stimulation.
Reduced incidence of diabetes
Cannabidiol can inhibit and delay the destruction of pancreatic insulin-producing cells and the production of inflammatory cytokines in diabetics. One study, which looked at 4 657 adult men and women, found that current marijuana use was associated with a decrease in 16% fasting insulin levels and a reduced waist circumference, a factor related to the onset of diabetes.
These data reinforce the hypothesis that CBD, which is known to be safe for humans, can eventually be used as a therapeutic agent for the treatment of cancer. early stage 1 diabetes of the disease.
Improved heart health
Studies show that CBD reduces heart rate and blood pressure in response to anxiety or stressful situations. The CBD has also influenced the function of white blood cells and platelet aggregation. We even find him to be therapeutic in cases of stroke. A number of preclinical studies have also shown beneficial effects of CBD in a range of disorders of the cardiovascular system.
However, further work is needed to demonstrate the ability of the CBD to prevent the development of heart and vascular disorders in humans.
Promotes bone growth
Although much less well known, our bones also have poorly studied cannabinoid receptors. CBD could improve the healing of broken limbs in mice. The CB1 receptor regulates maximal bone mass through the effects of osteoclasts, bone resorption and age-related bone loss. This means that the CBD administered has helped strengthen the fracture callus, the cartilage that regulates the fracture.
CBD and THC were tested, but only CDB-activated genetic pathways that also increase the collagen structure.
Studies have revealed that antidepressant effects of CBD were rapid, continuous, and comparable to those of a common tricyclic drug, imipramine, also known as Tofranil.
Treatment of inflammatory bowel diseases
Studies show that CBD can be a good candidate for normalizing intestinal motility in patients with inflammatory bowel disease.
CBD can reduce the severity of intestinal inflammation by theactivation of the gamma receptor. This one activated by proliferating peroxisomes (PPAR-gamma).
Protection against bacteria
CBD has shown some antimicrobial activity against Staphylococcus aureus resistant to methicillin (MRSA), a bacterium that causes infections that are difficult to treat.
Cannabidiol can protect against mad cow disease
Studies show that cannabidiol inhibits prions, the proteins that cause life-threatening neurodegenerative diseases such as Creutzfeldt-Jakob and mad cow disease.
CBD (combined with a TRPV-1 blocker) reduced the symptoms of dyskinesia in the mouse. CBD reduces the production of inflammatory markers.
Compared to the baseline, CBD decreased the amounts of key enzymes that cause dyskinesia. CBD, in combination with a TRPV-1 antagonist, reduces dyskinesia by acting on CB1 and PPAR gamma receptors. In sum, CBD reduces the expression of inflammatory markers COX-2 and NF-kB.
Help in the treatment of insomnia
Research suggests that taking CBD before bedtime improves sleep in people with insomnia. It could help sleep through its relaxing and anxiolytic effects.
In fact, cannabis users with insomnia prefer much higher strains of CBD as a sleep aid and are less likely to become addicted
Treatment of alcohol and other drug use disorders
Studies suggest that CBD could be therapeutic for disorders related to alcohol consumption and other drugs. CBD is effective against mental and psychological health disorders, includingaddiction "harmful". Drinking a lot of alcohol for many years causes alcoholic liver problems by constantly raising inflammation levels.
The anti-inflammatory properties of THC and CBD can predict that cannabis use could reduce the inflammation caused by alcohol, and thus help prevent the development of liver disease.
Help quit smoking
Research suggests that inhalation of cannabidiol for a week could reduce the number of cigarettes fumes of about 40%, without increasing the need for nicotine.
CBD is polypharmacological. Which means that it can affect multiple and different ways at the same time in the body. The main receivers are involved during thestop smoking, and this can be considered brutal. And, of course, CBD will be the perfect candidate as a palliative for nicotine and therefore for smoking.
Play a role in psoriasis
CBD reduces the growth of cutaneous cells (keratinocytes), playing a potential role in the psoriasis treatment. There are several independent, third-party studies that have shown that CBD-infused topicals can help relieve the itching, swelling, and redness associated with CBD.eczema and other inflammatory skin conditions.
Can treat acne
CBD decreases lipid synthesis and proliferation of human sebaceous glands, and has an anti-inflammatory effect on the sebaceous glands, thus having potential as a therapeutic agent in the treatment of the sebaceous glands.acne .
Dosage, and side effects
CBD is generally well tolerated and safe in high doses, and its use is chronic in humans. However, pronounced doses of CBD can mimic serotonin, which appears to increase the psychoactive effects of THC. And at very high doses, CBD can actually cause anxiety (via activation of TRPV1 receptors).
150 mg CBD oil and twice a day relieves anxiety and inflammation. To protect the brain (as in the case of Alzheimer's disease) and reduce inflammation and muscle contractions (MS), doses of 100 to 600 mg of CBD have been used in clinical studies. 300 mg per day was enough to reduce anxiety in clinical studies. But above 400 mg, CBD becomes less effective for anxiety, but better for pain relief.
Doses up to 800 mg of CBD per day have been used to treat psychosis and schizophrenia. The highest doses of CBD used in the studies were up to 3,5 g CBD oil per day for very severe seizures in children and young adults with epilepsy.